The NoSpamProxy Intranet role fails to start if the NoSpamProxy server is configured to use the TLS protocol exclusively in version 1.2 for connection encryption.
The problem is triggered by the version of Microsoft SQL Server used. For TLS 1.2 to work as the sole encryption protocol, your SQL Server must support encryption with TLS 1.2.
The following article describes the version requirements for Microsoft SQL Server TLS 1.2:
Please note that the exclusive use of TLS 1.2 as connection encryption does not reflect the settings we recommend as it may compromise compatibility. A corresponding message is displayed under Issues on the Management Console home page.